Hideki Nagase

ATP-sensitive K+ channel in the mitochondrial inner membrane

I Inoue, Hideki Nagase, Tomihiko Higuti · Nature · 1991 · 753 citations

Life Sciences, Biochemistry, Biophysics +14

Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models

Nozomu Tanaka, Kazuki Sakamoto, Hiroyuki Okabe et al. · Oncology Reports · 2014 · 142 citations · Full text

Medicine, Oncology, Pharmacology +13

Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin

Hideki Nagase, Keiichi Enjyoji, Kazuhisa Minamiguchi et al. · Blood · 1995 · 102 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Acquired resistance to trastuzumab/pertuzumab or to T‐DM1 in vivo can be overcome by HER2 kinase inhibition with TAS0728

Hiroki Irie, Rumi Kawabata, Yayoi Fujioka et al. · Cancer Science · 2020 · 37 citations · Full text

Medicine, Oncology, Pharmacology +17

DHG, A NEW DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN, EXERTS AN ANTITHROMBOTIC EFFECT WITH LESS BLEEDING THAN UNFRACTIONATED OR LOW MOLECULAR WEIGHT HEPARIN, IN RATS

Kenji Kitazato, Kenji Kitazato, Keiko T. Kitazato et al. · Thrombosis Research · 1996 · 34 citations

Medicine, Hematology, Pharmacotherapy +11