Nature loves nitrogen heterocycles

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +10

Patellamide A and C biosynthesis by a microcin-like pathway in <i>Prochloron didemni</i> , the cyanobacterial symbiont of <i>Lissoclinum patella</i>

Eric W. Schmidt, James T. Nelson, David A. Rasko et al. · Proceedings of the National Academy of Sciences · 2005 · 570 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Telomestatin, a Novel Telomerase Inhibitor from <i>Streptomyces anulatus</i>

Kazuo Shin‐ya, Konstanty Wierzba, Ken‐ichi Matsuo et al. · Journal of the American Chemical Society · 2001 · 499 citations

Life Sciences, Biochemistry, Molecular Biology +9

Structure of isopenicillinN synthase complexed with substrate and the mechanism ofpenicillin formation

Peter L. Roach, I.J. Clifton, Charles M. H. Hensgens et al. · Nature · 1997 · 433 citations

Life Sciences, Biochemistry, Molecular Biology +6

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

Joerg Harms, Daniel N. Wilson, Frank Schluenzen et al. · Molecular Cell · 2008 · 310 citations · Full text

Life Sciences, Microbiology, Molecular Biology +12