Connective Synthesis of Spirovetivanes: Total Synthesis of (±)‐Agarospirol, (±)‐Hinesol and (±)‐α‐Vetispirene

Abstract

Abstract A concise, connective synthesis of naturally occurring spirovetivanes 1 and 3 , in racemic form, is presented. This novel approach involves the efficient assembly of the advanced intermediate 12 through a unique spiroannulation protocol. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)