JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

Life Sciences, Cell Biology, Genetics +16

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick · Nature · 1999 · 3.6K citations

Medicine, Cell Biology, Oncology +14

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard, Masahiko Hibi, I‐Huan Wu et al. · Cell · 1994 · 3.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine V. Unitarian theory of the origin of the four epithelial cell types

Hazel Cheng, C. P. Leblond · American Journal of Anatomy · 1974 · 1.7K citations

Life Sciences, Cell Biology, Endocytosis +13

Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

Eek‐hoon Jho, Tong Zhang, Claire Domon–Dell et al. · Molecular and Cellular Biology · 2002 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16