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A FACILE SYNTHESIS OF CARBOXAMIDES BY USING 1-METHYL-2-HALOPYRIDINIUM IODIDES AS COUPLING REAGENTS
133
Citations
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References
1975
Year
Cross-coupling ReactionEngineeringFree Carboxylic Acids1-Methyl-2-halopyridinium IodidesOrganic ChemistryCatalysisChemistryHalogenationCoupling ReagentsSynthetic ChemistryBiomolecular EngineeringAbstract Carboxamides
Abstract Carboxamides are rapidly formed in high yields by equimolar reactions of free carboxylic acids and amines, involving secondary or tertiary alkyl substituted acids and amines, with 1-methyl-2-halopyridinium iodides in the presence of tri-n-butylamine.
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