Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions

Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Joel L. Moake, Christine K. Rudy, Joseph H. Troll et al. · New England Journal of Medicine · 1982 · 1.1K citations

Medicine, Hematology, Pathology +17

ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions

Jing-fei Dong, Joel L. Moake, Leticia Nolasco et al. · Blood · 2002 · 848 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation.

Joel L. Moake, NA Turner, NA Stathopoulos et al. · Journal of Clinical Investigation · 1986 · 610 citations · Full text

Medicine, Cell Biology, Hematology +17

Shear-dependent changes in the three-dimensional structure of human von Willebrand factor

CA Siediecki, BJ Lestini, KK Kottke-Marchant et al. · Blood · 1996 · 604 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers

Maneesh Arya, Bahman Anvari, Gabriel M. Romo et al. · Blood · 2002 · 314 citations · Full text

Life Sciences, Biology, Molecular Biology +16