Effect of Oophorectomy on Survival After Breast Cancer in<i>BRCA1</i>and<i>BRCA2</i>Mutation Carriers

Abstract

Oophorectomy is associated with a decrease in mortality in women with breast cancer and a BRCA1 mutation. Women with estrogen receptor-negative breast cancer and a BRCA1 mutation should undergo oophorectomy shortly after diagnosis.