Iminosugars: from botanical curiosities to licensed drugs

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

Timothy M. Cox, Robin Lachmann, C. E. Hollak et al. · The Lancet · 2000 · 744 citations

Medicine, Pharmacology, Pharmacotherapy +4

Accelerated transport and maturation of lysosomal α–galactosidase A in Fabry lymphoblasts by an enzyme inhibitor

Jianqiang Fan, Naoki Asano, Yoshiyuki Suzuki · Nature Medicine · 1999 · 613 citations

Life Sciences, Biochemistry, Molecular Biology +14

Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study

Marc C. Patterson, Darleen Vecchio, Helena Prady et al. · The Lancet Neurology · 2007 · 610 citations · Full text

Pharmacy, Internal Medicine, Pharmacotherapy +3

N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.

Frances M. Platt, Gabrielle R. Neises, Raymond A. Dwek et al. · Journal of Biological Chemistry · 1994 · 453 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Loco Intoxication: Indolizidine Alkaloids of Spotted Locoweed ( <i>Astragalus lentiginosus</i> )

Russell J. Molyneux, Lynn F. James · Science · 1982 · 413 citations

Life Sciences, Botany, Pharmacology +11