Endorphins are located in the intermediate and anterior lobes of the pituitary gland, not in the neurohypophysis

<b>Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide</b>

R. B. Merrifield · Journal of the American Chemical Society · 1963 · 7.6K citations

Natural Sciences, Biochemistry, Chemistry +6

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 981 citations

Medicine, Neuroscience, Pharmacology +14

Opioid Peptides Endorphins in Pituitary and Brain

Avram Goldstein · Science · 1976 · 516 citations

Life Sciences, Endocrinology, Neuroscience +12

An endogenous morphine-like factor in mammalian brain

Gavril W. Pasternak, Robert Goodman, Solomon H. Snyder · Life Sciences · 1975 · 393 citations

Life Sciences, Neurobiology, Neuroscience +14