Opioid Peptides Endorphins in Pituitary and Brain

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Opiate Receptor: Demonstration in Nervous Tissue

Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations

Medicine, Neuroscience, Pharmacology +10

Purification and properties

Brian M. Cox, K E Opheim, H. Teschemacher et al. · Life Sciences · 1975 · 1.7K citations

Stereospecific Binding of the Potent Narcotic Analgesic [ ³ H]Etorphine to Rat-Brain Homogenate

Eric J. Simon, Jacob M. Hiller, Irit Edelman · Proceedings of the National Academy of Sciences · 1973 · 1.1K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 981 citations

Medicine, Neuroscience, Pharmacology +14