Opioid Peptides Endorphins in Pituitary and Brain

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Neurophysiology, Neuroanatomy, Related Pentapeptides +11

Opiate Receptor: Demonstration in Nervous Tissue

Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations

Powerful Opiate Antagonist, Psychoactive Drug, Medicine +12

Purification and properties

Brian M. Cox, K E Opheim, H. Teschemacher et al. · Life Sciences · 1975 · 1.7K citations

Biochemistry, Water Purification, Purification Method +2

Stereospecific Binding of the Potent Narcotic Analgesic [ ³ H]Etorphine to Rat-Brain Homogenate

Eric J. Simon, Jacob M. Hiller, Irit Edelman · Proceedings of the National Academy of Sciences · 1973 · 1.1K citations · Full text

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 980 citations

Molecular Pharmacology, Psychoactive Drug, Pharmacological Study +13