Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

Actin Stress Fibers, Protein Function, Signal Transduction +13

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

Omar A. Coso, M Chiariello, Jin‐Chen Yu et al. · Cell · 1995 · 1.6K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +8

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Audrey Minden, Anning Lin, François-Xavier Claret et al. · Cell · 1995 · 1.5K citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation

Shubha Bagrodia, Benoît Dérijard, Roger J. Davis et al. · Journal of Biological Chemistry · 1995 · 635 citations · Full text

Pak-mediated Signaling, Immunology, Immunotherapy +19

rac, a novel ras-related family of proteins that are botulinum toxin substrates

John Didsbury, R F Weber, Gary Bokoch et al. · Journal of Biological Chemistry · 1989 · 572 citations · Full text