Concepedia

The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation

Ji‐Hee Kim, Hee-Jun Na, Ji-Yoon Kim, Kwon‐Soo Ha, Hansoo Lee, Hun‐Taeg Chung, Ho Jeong Kwon, Young‐Guen Kwon, Young‐Myeong Kim

Free Radical Biology and Medicine · 2008 · 261 citations · 36 references

DOI

Concepts

References

36

Lycopene as the most efficient biological carotenoid singlet oxygen quencher

Paolo Di Mascio, Stephan Kaiser, Helmut Sies · Archives of Biochemistry and Biophysics · 1989 · 2.2K citations

, , +10

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al. · Nature · 1999 · 2.2K citations

, , +16

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

Julia A. Romashkova, Sergei S. Makarov · Nature · 1999 · 1.8K citations

, , +11

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

, , +17

Reversible Inactivation of the Tumor Suppressor PTEN by H2O2

Seung-Rock Lee, Kap‐Seok Yang, Jaeyul Kwon et al. · Journal of Biological Chemistry · 2002 · 1K citations · Full text

, , +17