Influence of microbubble surface charge on capillary transit and myocardial contrast enhancement

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Alexander L. Klibanov, Kazuo Maruyama, Vladimir P. Torchilin et al. · FEBS Letters · 1990 · 2K citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Indicator Transit Time Considered as a Gamma Variate

Howard Thompson, C F Starmer, Robert E. Whalen et al. · Circulation Research · 1964 · 587 citations · Full text

Engineering, Radiology, Stochastic Processes +6

Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target

A.L. Klibanov, Kazuo Maruyama, Anne Marie Beckerleg et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 483 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity

Vladimir P. Torchilin, Vladimir G. Omelyanenko, Mikhail Papisov et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1994 · 465 citations

Natural Sciences, Biochemistry, Biomedical Engineering +16

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.

Arcadio Chonn, Sean C. Semple, P.R. Cullis · Journal of Biological Chemistry · 1992 · 461 citations · Full text

Life Sciences, Biochemistry, Pharmacokinetics +17