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Amathaspiramides A−F, Novel Brominated Alkaloids from the Marine Bryozoan <i>Amathia </i><i>w</i><i>ilsoni</i>
102
Citations
5
References
1999
Year
Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicineStructure ElucidationMedicinal FungiNew Zealand CollectionOrganic ChemistryAmathaspiramide FAmathaspiramide CChemistryNovel Brominated AlkaloidsAmathaspiramides A−fPharmacologyPharmaceutical ChemistryDrug DiscoveryDrug Analysis
A series of six new dibrominated alkaloids, amathaspiramides A−F (1−6), have been isolated from a New Zealand collection of the marine bryozoan Amathia wilsoni. An X-ray crystallographic structural determination of amathaspiramide F (6) revealed it to be an epimer of amathaspiramide C (3). These data, in addition to the results of NOESY NMR experiments were used to infer the absolute configuration of the amathaspiramides.
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