Concepedia

Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver

Ben Z. Stanger, Akemi Tanaka, Douglas A. Melton

Nature · 2007 · 388 citations · 33 references

DOI

Concepts

References

33

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez et al. · Nature · 2004 · 2.2K citations

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Insulin-promoter-factor 1 is required for pancreas development in mice

Jörgen Jönsson, Lena Carlsson, Helena Edlund · Nature · 1994 · 1.8K citations

, , +13

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Martin F. Offield, Tom L. Jetton, Patricia A. Labosky et al. · Development · 1996 · 1.5K citations

, , +16

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Guoqiang Gu, Jolanta Dubauskaite, Douglas A. Melton · Development · 2002 · 1.5K citations

, , +16

Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes

Eric Rulifson, Seung K. Kim, Roel Nusse · Science · 2002 · 1.1K citations

, , +17