Concepedia

Conversion of the Enantiomers of Spiro[4.4]nonane-1,6-Diol into Both Epimeric Carbaspironucleosides Having Natural C1‘ Absolute Configuration

Leo A. Paquette, Ryan E. Hartung, David J. France

Organic Letters · 2003 · 16 citations · 20 references

DOI

Concepts

Abstract

[reaction: see text] The enantiomers of spiro[4.4]nonane-1,6-diol have been transformed by different reaction pathways into the two possible carbaspironucleoside epimers with natural C1' absolute stereochemistry.

References

20

Lanthanides in organic chemistry. 1. Selective 1,2 reductions of conjugated ketones

Jean Louis Luche · Journal of the American Chemical Society · 1978 · 1.2K citations

, , +7

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

Hiroaki Mitsuya, S Broder · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

, , +16

Allylic oxidation with 3,5-dimethylpyrazole. Chromium trioxide complex steroidal .DELTA.5-7-ketones

William G. Salmond, M. A. BARTA, Jeffrey L. Havens · The Journal of Organic Chemistry · 1978 · 281 citations

, , +6

Potent and selective activity of a new carbocyclic nucleoside analog (Carbovir: NSC 614846) against human immunodeficiency virus In vitro

Robert Vince, Hua Mei, Jay Brownell et al. · Biochemical and Biophysical Research Communications · 1988 · 231 citations · Full text

, , +13

Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.

R. T. BORCHARDT, B T Keller, Usha Patel-Thombre · Journal of Biological Chemistry · 1984 · 185 citations · Full text

, , +8