Chromosomal Dynamics at the Shh Locus: Limb Bud-Specific Differential Regulation of Competence and Active Transcription

Capturing Chromosome Conformation

Job Dekker, Karsten Rippe, Martijn Dekker et al. · Science · 2002 · 3.7K citations

Sonic hedgehog mediates the polarizing activity of the ZPA

Robert D. Riddle, Randy L. Johnson, Ed Laufer et al. · Cell · 1993 · 2.3K citations

Biology, Developmental Biology, Neuroanatomy +5

Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

Bas Tolhuis, Robert‐Jan Palstra, Erik Splinter et al. · Molecular Cell · 2002 · 1.3K citations · Full text

Protein Function, Signal Transduction, Protein Folding +7

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

Laura A. Lettice · Human Molecular Genetics · 2003 · 1.2K citations · Full text

Genetics, Genomic Mechanism, Preaxial Polydactyly +18

Active genes dynamically colocalize to shared sites of ongoing transcription

Cameron S. Osborne, Lyubomira Chakalova, Karen Brown et al. · Nature Genetics · 2004 · 1.1K citations · Full text

Chromatin, Transcriptional Regulation, Active Genes +13