Concepedia

Temporal Control Of Differentiation

Temporal Control of Differentiation is a regulatory mechanism in developmental biology that governs the precise timing of cellular commitment to specific lineages during development, distinguishing it from spatial or signal-induced differentiation controls by emphasizing the temporal dimension of gene expression and signaling dynamics.

949

Publications

82.3K

Citations

3.9K

Authors

983

Institutions

Publications per year

2017–2026

156

Parents

Children

Publications

949

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Bruce Wightman, Ilho Ha, Gary Ruvkun · Cell · 1993 · 4.2K citations · Full text

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Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

Alla Grishok, Amy E. Pasquinelli, Darryl Conte et al. · Cell · 2001 · 1.9K citations · Full text

, , +12

Translating developmental time across mammalian species

Barbara Clancy, Richard B. Darlington, Barbara L. Finlay · Neuroscience · 2001 · 1.2K citations

, , +13

A Developmental Switch in the Response of DRG Neurons to ETS Transcription Factor Signaling

Simon Hippenmeyer, Eline Pecho‐Vrieseling, Markus W. Sigrist et al. · PLoS Biology · 2005 · 1.2K citations · Full text

, , +17

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

Gabriella Ficz, Miguel R. Branco, Stefanie Seisenberger et al. · Nature · 2011 · 1.1K citations

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1–5 of 949

Authors

3.9K

  1. VA
    Victor Ambros

    University of Massachusetts Chan Medical School, United States

    12 publications · 2.3K citations

    12

    h-index

  2. GR
    Gary Ruvkun

    Massachusetts General Hospital, United States

    8 publications · 7K citations

    8

    h-index

  3. CQ
    Chris Q. Doe

    Howard Hughes Medical Institute, United States

    6 publications · 959 citations

    6

    h-index

  4. FM
    Fiona M. Watt

    The Honourable Society of Lincoln's Inn, United Kingdom

    6 publications · 641 citations

    6

    h-index

  5. MB
    Michael B. Elowitz

    California Institute of Technology, United States

    6 publications · 1.8K citations

    6

    h-index

1–5 of 3.9K

Institutions

983

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    30 h-index

    109 publications

    18.6K citations

  2. Harvard University

    Cambridge, United States

    27 h-index

    81 publications

    15.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    162 publications

    11K citations

  4. California Institute of Technology

    Pasadena, United States

    21 h-index

    82 publications

    10K citations

  5. University of California, San Francisco

    San Francisco, United States

    20 h-index

    57 publications

    6.3K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    19 h-index

    58 publications

    3.9K citations

  7. Inserm

    Paris, France

    19 h-index

    110 publications

    6.4K citations

  8. University of Washington

    Seattle, United States

    18 h-index

    64 publications

    7.8K citations

1–8 of 983

Venues

  1. Development

    81 publications · 6.5K citations

    45

    h-index

  2. Developmental Biology

    68 publications · 5.7K citations

    43

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 68 publications · 6.5K citations

    42

    h-index

  4. Cell

    26 publications · 11.8K citations

    25

    h-index

  5. Genes & Development

    22 publications · 3.6K citations

    22

    h-index

1–5