Hydrogen peroxide inhibits formation of cartilage in chicken micromass cultures and decreases the activity of calcineurin: implication of ERK1/2 and Sox9 pathways

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>

Haruhiko Akiyama, Marie‐Christine Chaboissier, James F. Martin et al. · Genes & Development · 2002 · 1.7K citations · Full text

Life Sciences, Developmental Biology, Genetics +17

SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

Véronique Lefebvre, Wendong Huang, Vincent R. Harley et al. · Molecular and Cellular Biology · 1997 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

Annette Salmeen, Jannik N. Andersen, Michael P. Myers et al. · Nature · 2003 · 948 citations

Life Sciences, Biochemistry, Molecular Biology +13

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

Vincent M. Coghlan, Brian A. Perrino, Monique Howard et al. · Science · 1995 · 618 citations

Life Sciences, Biochemistry, Neuroscience +15

Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-κB

Xiaochun Bai, Di Lu, Jie Bai et al. · Biochemical and Biophysical Research Communications · 2004 · 565 citations

Medicine, Molecular Medicine, Bone Metabolism +11