Solid phase synthesis of oligo-α- and oligo-β-deoxynucleotidescovalently linked to an acridine

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Serge L. Beaucage, Marvin H. Caruthers · Tetrahedron Letters · 1981 · 2K citations

Pharmacy, Biochemistry, Molecular Biology +7

Polymer support oligonucleotide synthesis XVIII^1.2): use of<i>β</i>-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

N. D. SINHA, J. Biernat, J. F. A. McManus et al. · Nucleic Acids Research · 1984 · 848 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides.

U. Asseline, Marc Delarue, G. Lancelot et al. · Proceedings of the National Academy of Sciences · 1984 · 171 citations · Full text

Pharmacy, Biochemistry, Chemistry +17

Enzymatic amplification of translation inhibition of rabbit β-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents

Christian Cazenave, Nadine Loreau, Nguyen T. Thuong et al. · Nucleic Acids Research · 1987 · 163 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Selective inhibition of the cytopathic effect of type A influenza viruses by oligodeoxynucleotides covalently linked to an intercalating agent

Aurelio Zerial, Nguyen T. Thuong, Claude Hélène · Nucleic Acids Research · 1987 · 130 citations · Full text

Life Sciences, Microbiology, Molecular Biology +12