Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2?

Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell Monolayers

Jan Taipalensuu, Hans Törnblom, Greger Lindberg et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 444 citations

Medicine, Cell Biology, Pharmacology +13

Involvement of Human Organic Anion Transporting Polypeptide OATP-B (SLC21A9) in pH-Dependent Transport across Intestinal Apical Membrane

Daisuke Kobayashi, Takashi Nozawa, Kozue Imai et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 415 citations

Medicine, Biochemistry, Pharmacology +15

Inhibition of Transporter-Mediated Hepatic Uptake as a Mechanism for Drug-Drug Interaction between Cerivastatin and Cyclosporin A

Yoshihisa Shitara, Tomoo Itoh, Hitoshi Sato et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 340 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells

Annick Seithel, Johan Karlsson, Constanze Hilgendorf et al. · European Journal of Pharmaceutical Sciences · 2006 · 200 citations

Life Sciences, Cell Biology, Molecular Biology +14

Identification of the Hepatic Efflux Transporters of Organic Anions Using Double-Transfected Madin-Darby Canine Kidney II Cells Expressing Human Organic Anion-Transporting Polypeptide 1B1 (OATP1B1)/Multidrug Resistance-Associated Protein 2, OATP1B1/Multidrug Resistance 1, and OATP1B1/Breast Cancer Resistance Protein

Soichiro Matsushima, Kazuya Maeda, Chihiro Kondo et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 189 citations

Life Sciences, Biochemistry, Molecular Biology +17