Loss of heterozygosity and methylation of p16 in renal cell carcinoma

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +17

Prognostic significance of morphologic parameters in renal cell carcinoma

Susan Fuhrman, Larry C. Lasky, Catherine Limas · The American Journal of Surgical Pathology · 1982 · 2.7K citations

Medicine, Oncology, Pathology +16

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

Medicine, Genetics, Molecular Biology +17

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

James G. Herman, Farida Latif, Y Weng et al. · Proceedings of the National Academy of Sciences · 1994 · 1.5K citations

Medicine, Genetics, Oncology +17

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

James G. Herman, Adrian Merlo, Li Mao et al. · PubMed · 1995 · 1.4K citations

Medicine, Genetics, Oncology +17