Solid phase 5′-phosphorylation of oligonucleotides

Rapid chromatographic technique for preparative separations with moderate resolution

W. Clark Still, Michaël Kahn, Abhijit Mitra · The Journal of Organic Chemistry · 1978 · 5.8K citations

Pharmacy, Chemistry, Analytical Chemistry +8

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Serge L. Beaucage, Marvin H. Caruthers · Tetrahedron Letters · 1981 · 2K citations

Pharmacy, Biochemistry, Molecular Biology +7

Synthesis of deoxyoligonucleotides on a polymer support

Mark D. Matteucci, M. H. CARUTHERS · Journal of the American Chemical Society · 1981 · 881 citations

Natural Sciences, Chemistry, Nucleic Acid Chemistry +6

Polymer support oligonucleotide synthesis XVIII^1.2): use of<i>β</i>-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

N. D. SINHA, J. Biernat, J. F. A. McManus et al. · Nucleic Acids Research · 1984 · 848 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides

Lincoln J. McBride, Marvin H. Caruthers · Tetrahedron Letters · 1983 · 513 citations

Life Sciences, Biochemistry, Molecular Biology +10