Transplantation · 1984 · 30 citations · 0 references
MedicineImmunologyNephrologyKidney TransplantationTransplant ImmunologyTransplant SurgeryAllograft RejectionCorticosteroid Use In TransplantationImmunosuppression In Kidney TransplantationImmunosuppression ManagementTransplant PharmacologyTransplant RejectionImmunosuppressive CompoundsKidney Transplant ImmunosuppressionRenal Transplant CareRenal Transplant RejectionRenal Transplant Surgery
Bredinin, a new nucleoside antibiotic isolated from Eupenicillium brefeldianum, and steroids were used as immunosuppressive agents in 31 renal transplant patients; 17 of them received grafts from living-related donors and 14 from cadavers. The one-year graft survival rates were 100% in renal recipients from living donors and 69.2% in cadaver kidney recipients. There was no serious complication from the use of these immunosuppressive agents.