Concepedia

SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion

Anastassios Economou, William Wickner

Cell · 1994 · 525 citations · 52 references

DOI

Concepts

References

52

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

, , +9

Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril

Mary Ann K. Markwell, Colin Fox · Biochemistry · 1978 · 897 citations

, , +10

The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane

F. Ulrich Hartl, Stewart H. Lecker, Joseph P. Hendrick et al. · Cell · 1990 · 564 citations

, , +8

The ATPase activity of secA is regulated by acidic phospholipids, secY, and the leader and mature domains of precursor proteins

Roland Lill, William Dowhan, William Wickner · Cell · 1990 · 552 citations

, , +10

The purified E. coli integral membrane protein is sufficient for reconstitution of SecA-dependent precursor protein translocation

Lorna Brundage, Joseph P. Hendrick, Arnold J. M. Driessen et al. · Cell · 1990 · 516 citations

, , +11