Antmaemophilic Factor A (F VIII) and Serum Fibrin‐Fibrinogen Degradation Products in Hepatic Cirrhosis

Abstract

Several coagulation parameters were examined in 82 patients with hepatic cirrhosis. An increase of F VIII levels was found in 72 % of the cases. This raise was not correlated with the gravity, nor with the etiology of the hepatic cirrhosis. Increased serum fibrin‐flbrinogen degradation products were found in 11 cases (13 %). Only 3 of them also had a hypofibrinogenaemia. It is concluded that the frequency and the intensity of clinically important disseminated intravascular coagulation or of primary fibrinolysis, both described in hepatic cirrhosis, are quite low.