Concepedia

The mGlu5 receptor antagonists MPEP and MTEP attenuate behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons in rats

Kurt Rasmussen, H. Martin Martin, James E. Berger, Matthew A. Seager

Neuropharmacology · 2004 · 38 citations · 47 references

DOI

Concepts

References

47

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

Keith A. Trujillo, Huda Akil · Science · 1991 · 1.2K citations

, , +17

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine

George K. Aghajanian · Nature · 1978 · 800 citations

, , +14

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

, , +7

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

Ryuichi Shigemoto, Sakashi Nomura, Hitoshi Ohishi et al. · Neuroscience Letters · 1993 · 520 citations

, , +14

Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

K. Rasmussen, DB Beitner-Johnson, JH Krystal et al. · Journal of Neuroscience · 1990 · 442 citations · Full text

, , +17