Enterotrophic Effect of Insulin‐Like Growth Factor‐I but not Growth Hormone and Localized Expression of Insulin‐Like Growth Factor‐I, Insulin‐Like Growth Factor Binding Protein‐3 and ‐5 mRNAs in Jejunum of Parenterally Fed Rats

Abstract

The GH resistance observed in the jejunal mucosa of TPN rats cannot be fully explained by inadequate nutrition. The expression of IGFBP-5 in the lamina propria suggests it may modulate the enterotrophic action of exogeneous IGF-I.