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Inhibition of TNF receptor signaling by anti-TNFα biologicals primes naïve CD4+ T cells towards IL-10+ T cells with a regulatory phenotype and function

Anti-tnfα Biologicals PrimesT-regulatory CellImmunologyImmune RegulationImmunologic MechanismCd4 T Cell ResponsesInnate ImmunityImmune SystemImmune DysregulationInflammationTumor ImmunityCell SignalingRegulatory T Cell BiologyImmune SurveillanceHumoral ImmunityT Cell ImmunityIl-10+ T CellsCell BiologyCytokineImmune Cell DevelopmentTnf ReceptorCellular Immune ResponseMedicine