Inhibition of <scp>I</scp>g<scp>E</scp> binding to cross‐reactive carbohydrate determinants enhances diagnostic selectivity

Abstract

Eliminating the effect of IgEs directed against CCDs by inhibition leads to a significant reduction in false-positive in vitro test results without lowering sensitivity towards relevant sensitizations. Application of the CCD blocker may be worthwhile wherever natural allergen extracts or components are used.