Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

Karen S. Sellins, John Cohen · The Journal of Immunology · 1987 · 925 citations

Medicine, Cell Biology, Molecular Biology +16

Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells.

Laurence Gamet‐Payrastre, Pengfei Li, Solange Lumeau et al. · PubMed · 2000 · 619 citations

Medicine, Oncology, Pharmacology +17

Food‐derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis

Michelle Mouria, Anna S. Gukovskaya, Yoon Jung et al. · International Journal of Cancer · 2002 · 273 citations

Medicine, Oncology, Pharmacology +17

A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway

Yasujiro Morimitsu, Yoko Nakagawa, Kazuhiro Hayashi et al. · Journal of Biological Chemistry · 2002 · 272 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane

Carmela Fimognari · Carcinogenesis · 2002 · 235 citations · Full text

Medicine, Oncology, Pharmacology +15