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The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model

Knockout MouseNeurodegenerative DiseasesGaa Triplet-repeatNeuroanatomyGeneticsHuman Fxn LocusDegenerative DiseaseNeuroscienceTransgenic Mouse ModelCentral Nervous SystemMolecular NeurobiologyMedicineNeurogenetics