Scandinavian Journal of Gastroenterology · 1997 · 161 citations · 16 references
MedicineClinical SciencesInternal MedicineGastroenterologyGeneral Internal MedicineHealth InsuranceAmbulatory Care UtilizationGastrointestinal InflammationHealthcare Cost AnalysisInflammatory Bowel DiseaseInflammatory Bowel Disease CareAmbulatory Care CostsAmbulatory Care UseChronic Disease Cost AnalysisDirect Nonmedical CostsDirect Treatment CostsHealth Care EconomicsHealth Care Resource Use MeasurementSickness Experience
BACKGROUND: Inflammatory bowel disease (IBD) has highly variable course and severity. Since comprehensive data on its impact are scarce, we analyzed all IBD care and costs in Sweden (population, 8.8 million). METHODS: A cross-sectional observational study, using national registers and surveys on ambulatory care, hospital admissions, medication, sickness leave, and early retirement for IBD in 1994, was carried out. We calculated direct health care costs and indirect 1-year costs caused by morbidity. RESULTS: Ambulatory care was concentrated to specialists in internal medicine at hospitals. One-fourth of the patients accounted for 48% of 1994 hospital admissions. Medication was predominantly aminosalicylates and steroids. Sickness leave episodes were long--on average, 6 weeks. Although uncommon, early retirements lasted 14 years on average. With regard to the underlying prevalence, the use of health care and compensations by Crohn's disease patients was two to four times that of patients with ulcerative colitis. Morbidity took 68% of total costs. Among direct costs, admissions accounted for 58%. Neither complications nor surveillance added much. CONCLUSION: Ulcerative colitis is twice as common as Crohn's disease. In health care use, these roles are reversed. Since morbidity causes two-thirds of the costs, comprehensive analyses, including indirect costs, are necessary when evaluating new diagnostics and therapies.
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Ulcerative Colitis and Colorectal Cancer
Anders Ekbom, Charles G. Helmick, Matthew M. Zack et al. · New England Journal of Medicine · 1990 · 1.8K citations · Full text
Increased risk of large-bowel cancer in Crohn's disease with colonic involvement
Anders Ekbom, H-O Adami, C. G. Helmick et al. · The Lancet · 1990 · 705 citations
Ulcerative colitis and colorectal cancer
Anders Ekbom · Biomedicine & Pharmacotherapy · 1991 · 419 citations