Bulletin of the Chemical Society of Japan · 1988 · 10 citations · 1 references
Natural SciencesChemistryOrganic ChemistryOrganometallic ChemistrySpectroscopyCarboxylic AcidsChiral ChromatographyChiral SeparationOptical SpectroscopyAliphatic Carboxylic AcidsAromatic Carboxylic AcidsChiral Carboxylic AcidsCrystallizationFractional Crystallization
Abstract (±)-α-Ethylbenzylamine ((±)-1) was efficiently resolved into a pair of enantiomers by fractional crystallization as its cis-2-benzamidocyclohexanecarboxylic acid (2) salt. Moreover, it was found that each of both enantiomers was obtained by mutual resolution between (±)-1 and (±)-2. The optically active amine (1) was substantially capable of resolving a variety of chiral carboxylic acids.
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