Association between multidrug resistance 1 (MDR1) gene polymorphisms and therapeutic response to bromperidol in schizophrenic patients: A preliminary study

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

Medicine, Molecular Genetics, Pharmacology +15

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +16

The UKU side effect rating scale: A new comprehensive rating scale for psychotropic drugs and a cross‐sectional study of side effects in neuroleptic‐treated patients

Ole Christian Lingjærde, U. G. Ahlfors, Per Bech et al. · Acta Psychiatrica Scandinavica · 1987 · 1.7K citations

Pharmacy, Pharmacology, Pharmacotherapy +10

Expression of P-glycoprotein in Human Placenta: Relation to Genetic Polymorphism of the Multidrug Resistance (MDR)-1 Gene

Mizuho Tanabe, Ichiro Ieiri, Naoki Nagata et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 535 citations

Life Sciences, Genetics, Molecular Genetics +13