Coiled‐Coil Peptide‐Based Assembly of Gold Nanoparticles

Abstract

The coiled‐coil‐based assembly of gold nanoparticles (see Figure and cover) is demonstrated. Control over the assembly and disassembly of nanostructures is achieved under mild conditions (near‐neutral pH and ambient temperature). The flexibility in design afforded by varying the peptide sequence to produce coiled coils with different stabilities is also highlighted by the generation of more stable binary nanoparticle systems with controlled spacing and architecture.