Inhibition by dexmedetomidine of the activation of spinal dorsal horn glias and the intracellular ERK signaling pathway induced by nerve injury

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

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Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

Zhi‐Ye Zhuang, Peter Gerner, Clifford J. Woolf et al. · Pain · 2005 · 778 citations

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A Peptide c-Jun N-Terminal Kinase (JNK) Inhibitor Blocks Mechanical Allodynia after Spinal Nerve Ligation: Respective Roles of JNK Activation in Primary Sensory Neurons and Spinal Astrocytes for Neuropathic Pain Development and Maintenance

Zhi‐Ye Zhuang, Yeong‐Ray Wen, De-Ren Zhang et al. · Journal of Neuroscience · 2006 · 523 citations · Full text

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