Establishment of Optimized MDCK Cell Lines for Reliable Efflux Transport Studies

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Alfred H. Schinkel, Johan W. Jonker · Advanced Drug Delivery Reviews · 2012 · 1.2K citations

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