Concepedia

MDM2 SNP309 and p53 Arg72Pro in cutaneous melanoma: association between SNP309 GG genotype and tumor Breslow thickness

Mario Capasso, Fabrizio Ayala, Rosa Anna Avvisati, Roberta Russo, Antonella Gambale, Nicola Mozzillo, Paolo A. Ascierto, Achille Iolascon

Journal of Human Genetics · 2010 · 14 citations · 27 references

DOI

Concepts

References

27

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Thickness, Cross-Sectional Areas and Depth of Invasion in the Prognosis of Cutaneous Melanoma

Alexander Breslow · Annals of Surgery · 1970 · 2.4K citations

, , +14

Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System

Charles M. Balch, Seng‐Jaw Soong, Jeffrey E. Gershenwald et al. · Journal of Clinical Oncology · 2001 · 2.4K citations

, , +17

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

Gareth L. Bond, Wenwei Hu, Elisabeth E. Bond et al. · Cell · 2004 · 1.3K citations · Full text

, , +15

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner

Gareth L. Bond, Kim M. Hirshfield, Tomas Kirchhoff et al. · Cancer Research · 2006 · 287 citations

, , +17