Concepedia

A novel analog of antimicrobial peptide Polybia-MPI, with thioamide bond substitution, exhibits increased therapeutic efficacy against cancer and diminished toxicity in mice

Wei Zhang, Jia Li, Liwei Liu, Kairong Wang, Jingjing Song, Jiexi Yan, Zhen‐Ya Li, Bangzhi Zhang, Rui Wang

Peptides · 2010 · 60 citations · 28 references

DOIFull text

Open access

Concepts

References

28

Structural Basis of the Drug-binding Specificity of Human Serum Albumin

J. Ghuman, Patricia A. Zunszain, I. Petitpas et al. · Journal of Molecular Biology · 2005 · 1.9K citations

, , +12

Role of Peptide Hydrophobicity in the Mechanism of Action of α-Helical Antimicrobial Peptides

Yuxin Chen, Michael T. Guarnieri, Adriana I. Vasil et al. · Antimicrobial Agents and Chemotherapy · 2006 · 747 citations · Full text

, , +16

Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index

Yuxin Chen, Colin T. Mant, Susan Walker Farmer et al. · Journal of Biological Chemistry · 2005 · 598 citations · Full text

, , +16

Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides

Margitta Dathe, Torsten Wieprecht, Heike Nikolenko et al. · FEBS Letters · 1997 · 409 citations · Full text

, , +17

Antimicrobial Activity and Protease Stability of Peptides Containing Fluorinated Amino Acids

He Meng, Krishna Kumar · Journal of the American Chemical Society · 2007 · 244 citations

, , +17