Concepedia

Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb

Ying Shi, Zhen Li, Yuan-Biao Qiao, Jun Lin

Journal of Chromatography B · 2012 · 48 citations · 15 references

DOI

Concepts

References

15

Succinimide Formation from Aspartyl and Asparaginyl Peptides as a Model for the Spontaneous Degradation of Proteins

Robert C. Stephenson, Steven Clarke · Journal of Biological Chemistry · 1989 · 518 citations · Full text

, , +14

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

Damian J. Houde, Yucai Peng, Steven A. Berkowitz et al. · Molecular & Cellular Proteomics · 2010 · 393 citations · Full text

, , +17

Characterizing biological products and assessing comparability following manufacturing changes

Arthur J. Chirino, Anthony R. Mire‐Sluis · Nature Biotechnology · 2004 · 364 citations

, , +14

Structure and Stability Changes of Human IgG1 Fc as a Consequence of Methionine Oxidation

Dingjiang Liu, Da Ren, Holly S. Huang et al. · Biochemistry · 2008 · 262 citations

, , +13

C‐terminal lysine variants in fully human monoclonal antibodies: Investigation of test methods and possible causes

Lawrence W. Dick, Difei Qiu, David Mahon et al. · Biotechnology and Bioengineering · 2008 · 156 citations

, , +11