New England Journal of Medicine · 1978 · 78 citations · 23 references
MedicineInternal MedicinePathologyAlcohol ToxicologyHepatologyHepatotoxicologyAlcohol-related Liver ToxicityCirrhosisHepatic ImpairmentHepatic PathophysiologyLiver DiseaseLiver Function TestsAlcohol-induced Hepatic NecrosisAlcohol-induced HepatotoxicityAlcohol-related HepatotoxicityAlcohol-related Liver InjuryAlcoholic Liver Disease ProgressionEarly DiagnosisLiver Disease ComplicationsLiver Toxicity Of Alcohol
ALCOHOLISM is a medical problem with an increasingly detrimental impact on society. In the United States, the number of patients with alcoholism is now estimated to exceed 10 million, and in large urban areas, cirrhosis of the liver is the third major cause of death in persons between the ages of 25 and 65 years. This seminar discusses the pathogenesis of alcoholic liver injury, especially the development of cirrhosis, and a means to identify patients who are particularly susceptible to it. A test for early detection of high alcohol intake is also described.Role of Malnutrition in Alcoholic Liver Injury . . .
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The effect of normalization of plasma amino acids on hepatic encephalopathy in man.
J E Fischer, Harvey M. Rosen, Amin M. Ebeid et al. · PubMed · 1976 · 587 citations
Medicine, Biochemistry, Pharmacology +12
High Blood Acetaldehyde Levels after Ethanol Administration
Mark A. Korsten, Shohei Matsuzaki, Lawrence Feinman et al. · New England Journal of Medicine · 1975 · 519 citations
Pharmacy, Pharmacology, Toxicology +13
Pathogenesis of alcohol-induced accumulation of protein in the liver.
Enrique Baraona, M A Leo, Stephen A. Borowsky et al. · Journal of Clinical Investigation · 1977 · 308 citations · Full text