Concepedia

A Novel and Simple Synthesis of 9<i>H</i>-Pyrimido[4,5-<i>b</i>]indoles under Microwave Irradiation and Solvent-Free Conditions

Mehdi Adib, Bagher Mohammadi, Hamid Reza Bijanzadeh

Synlett · 2008 · 30 citations · 0 references

Concepts

Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryMicrowave-assisted SynthesisOrganic SynthesisRetrosynthetic AnalysisIndole ChemistryIndole DerivativesIndole SynthesisMicrowave Irradiation EffectsMicrowave-assisted Heterocycle SynthesisMicrowave-assisted Organic SynthesisMicrowave-assisted Solvent-free SynthesisSolvent-free Processing

Abstract

A novel synthesis of 9H-pyrimido[4,5-b]indoles is described from a simple microwave-assisted reaction between oxindoles and aryl nitriles under solvent-free conditions in good to excellent yields.