Effects of atorvastatin on chronic subdural hematoma: A preliminary report from three medical centers

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima et al. · Nature Medicine · 2000 · 1.4K citations

Life Sciences, Biochemistry, Pharmacology +12

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

Sawsan Youssef, Olaf Stüve, Juan C. Patarroyo et al. · Nature · 2002 · 1.1K citations

Life Sciences, Immunology, Neuroscience +15

Statins Have Biphasic Effects on Angiogenesis

Michael Weis, Christopher Heeschen, Alec Glassford et al. · Circulation · 2002 · 683 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

Jieli Chen, Zheng Gang Zhang, Yi Li et al. · Annals of Neurology · 2003 · 536 citations

Medicine, Neuroscience, Pharmacology +17

Atorvastatin Induction of VEGF and BDNF Promotes Brain Plasticity after Stroke in Mice

Jieli Chen, Chunling Zhang, Hao Jiang et al. · Journal of Cerebral Blood Flow & Metabolism · 2005 · 449 citations · Full text

Medicine, Neuroscience, Pharmacology +17