Genetic Variants and Strains of the Laboratory Mouse

Abstract

Book reviews seized to carry the factual descriptions into speculations about function and purpose.The seven excellent chapters include discussions on the analysis of MHC antigens at the protein and DNA levels, their organisation in the plasma membrane, restric- tion, properties of target cells, immune response genes and la antigens, MHC complement compo- nents, and finally speculations on evolution and function.This is not an easy book but it is certainly reward- ing and brings together many of the threads of current research into the 'fine structure' of the MHC, surely itself the Rossetta stone of immunopathology.