Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp‐derived fibroblasts

Abstract

These results suggest that HDAC inhibition is associated with myofibroblast differentiation and extracelluar matrix accumulation in nasal polyposis. TSA may be useful as an inhibitor of nasal polyp growth, and thus has potential to be used as a novel treatment option for nasal polyposis.