Expeditious synthesis of aziridine-based cofactor mimics

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.

Kenta Yoshiura, Yae Kanai, Atsushi Ochiai et al. · Proceedings of the National Academy of Sciences · 1995 · 665 citations · Full text

Medicine, Genetics, Oncology +17

DNA methylation represses transcription in vivo

Zahava Siegfried, Sharon Eden, Monica Mendelsohn et al. · Nature Genetics · 1999 · 356 citations

Life Sciences, Genetics, Molecular Biology +11

CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene.

Naoko Ohtani‐Fujita, Tsuyoshi Fujita, Akira Aoike et al. · PubMed · 1993 · 317 citations

Medicine, Genetics, Molecular Genetics +16

Association between CpG island methylation and microsatellite instability in colorectal cancer.

Nita Ahuja, Avinash Mohan, Qing Li et al. · PubMed · 1997 · 296 citations

Medicine, Genetics, Oncology +17