A genome-wide association identified the common genetic variants influence disease severity in β0-thalassemia/hemoglobin E

Principal components analysis corrects for stratification in genome-wide association studies

Alkes L. Price, Nick J. Patterson, Robert M. Plenge et al. · Nature Genetics · 2006 · 10.7K citations

Public Health, Biostatistics, Genetics +12

Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements

Josée Dostie, Todd Richmond, Ramy Arnaout et al. · Genome Research · 2006 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor <i>BCL11A</i>

Vijay G. Sankaran, Tobias Menne, Jian Xu et al. · Science · 2008 · 902 citations

Medicine, Genetics, Hematology +13

DNA polymorphisms at the <i>BCL11A</i> , <i>HBS1L-MYB</i> , and β- <i>globin</i> loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

Guillaume Lettre, Vijay G. Sankaran, Marcos Bezerra et al. · Proceedings of the National Academy of Sciences · 2008 · 555 citations · Full text

Life Sciences, Genetics, Hematology +16

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15

Stephan Menzel, Chad Garner, Fumihiko Matsuda et al. · Nature Genetics · 2007 · 530 citations

Life Sciences, Genetics, Molecular Genetics +7