Lung symptoms in pseudohypoaldosteronism type 1 are associated with deficiency of the α-subunit of the epithelial sodium channel

A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Cecilia M. Canessa, Laurent Schild, Gary Buell et al. · Nature · 1994 · 2K citations

Signal Transduction, Molecular Physiology, Biochemistry +13

A TEST FOR CONCENTRATION OF ELECTROLYTES IN SWEAT IN CYSTIC FIBROSIS OF THE PANCREAS UTILIZING PILOCARPINE BY IONTOPHORESIS

Lewis E. Gibson, Robert E. Cooke · PEDIATRICS · 1959 · 1.4K citations

Electrolyte Disorder, Medicine, Physiology +7

Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid

Jeffrey J. Smith, Sue M. Travis, E. Peter Greenberg et al. · Cell · 1996 · 1K citations · Full text

Microbial Disease, Pathogenesis, Pathology +6

Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice

Edith Hümmler, Pierre Barker, John T. Gatzy et al. · Nature Genetics · 1996 · 876 citations · Full text

Acute Lung Injury, Allergy, Lung Inflammation +10