Concepedia

Biomarkers of Caloric Restriction May Predict Longevity in Humans

George S. Roth, Mark A. Lane, Donald K. Ingram, Julie A. Mattison, Dariush Elahi, Jordan D. Tobin, Denis C. Muller, E. Jeffrey Metter

Science · 2002 · 446 citations · 5 references

DOI

Concepts

Abstract

The most robust intervention for slowing aging and maintaining health and function in animals is dietary caloric restriction (CR) ([1][1]). Although most studies of this phenomenon have been conducted in rodents and lower animals, data accumulating from rhesus monkeys suggest that CR may also be

References

5

The retardation of aging and disease by dietary restriction

Choice Reviews Online · 1989 · 1.5K citations

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Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle

Theodor A. Zainal, Terry D. Oberley, David B. Allison et al. · The FASEB Journal · 2000 · 215 citations

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Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points

Mark A. Lane, Sheldon S. Ball, Donald K. Ingram et al. · American Journal of Physiology-Endocrinology and Metabolism · 1995 · 140 citations

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Dietary Caloric Restriction Prevents the Age-Related Decline in Plasma Melatonin Levels of Rhesus Monkeys

George S. Roth, Vladimir Lesnikov, Marina Lesnikov et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 59 citations · Full text

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Calorie Restriction in Nonhuman Primates: Implications for Age-Related Disease Risk

Mark A. Lane, A. J. Black, Donald K. Ingram et al. · Journal of Anti-Aging Medicine · 1998 · 44 citations

, , +16